Ten years of scientific research and six years of experience in commercial cultivation, with more than 10,000 ha treated, have demonstrated that PMV®-01 is a reliable solution against damage caused by PepMV in a wide range of tomato types, from the smallest specialty tomatoes to large beef tomatoes, in both lit and unlit crops, across different substrate and soil types and under various climatic conditions. With the PMV®-01 vaccination strategy, the typical PepMV fruit symptoms are not observed. In addition, the 4 to 12% production losses caused by aggressive PepMV infection are significantly reduced.